個人簡介

姓名：趙國平

職稱：醫學博士，研究員，博士生導師

研究方向：當歸四逆湯方證研究

電子郵箱：tguo428@jnu.edu.cn

趙國平，男，漢族，南京中醫藥大學中醫學博士畢業，日本九州大學醫學部訪問學者、日本國立弘前大學基因研究中心高級訪問學者。曾擔任南京中醫藥大學國家中醫藥管理局中醫醫史文獻重點學科帶頭人、教育部國家級中醫醫史文獻重點學科帶頭人。2005年引進至太阳集团app首页，擔任太阳集团app首页國家中醫藥管理局中醫老年醫學重點學科帶頭人、太阳集团app首页國家中醫藥管理局中西醫結合基礎學術帶頭人。曾獲江蘇省青藍工程優秀青年骨幹教師、江蘇省333工程學術技術帶頭人、南京市優秀留學回國人員先進個人、江蘇省有突出貢獻青年專家，第七批全國老中醫藥專家學術經驗繼承指導老師；榮獲國家科技進步三等獎、國家中醫藥管理局中醫藥基礎研究一等獎、江蘇省中醫藥科技進步一等獎、中國政府出版獎。先後主持國家自然科學基金6項，發表論文100餘篇，編寫專著及教材19部。

更新時間：2024年1月21日

教學/科研成果

1.主持課題（近5年）：

（1） 國家自然科學基金面上-基于 artemin/GFRα3 調控 TRP 通道探讨當歸四逆湯鎮痛作用機制 （2019-2022，主持）

（2） 國家自然科學基金面上-基于抗炎-神經微循環的交互作用探讨當歸四逆湯對坐骨神經損傷的修複機制（2023-2026，主持）

2.發表論文（近3年）：

（1）Zheng Y. C., Zhao, J. J., Chang, S. Q., Zhuang, Z. F., Waimei, S., Li, X., Chen, Z. N., Jing, B., Zhang, D., Guoping Zhao*. β-Sitosterol Alleviates Neuropathic Pain by Affect Microglia Polarization through Inhibiting TLR4/NF-κB Signaling Pathway [J]. Journal of Neuroimmune Pharmacology, 2023.

（2）Zhang D., Li, X., Jing, B., Chen, Z., Shi, H., Zheng, Y., Chang, S., Sun, J., Guoping Zhao*.. alpha-Asarone attenuates chronic sciatica by inhibiting peripheral sensitization and promoting neural repair [J]. Phytotherapy Research, 2023, 37(1): 151-62.

（3）Zhang D., Jing, B., Chen, Z. N., Li, X., Shi, H. M., Zheng, Y. C., Chang, S. Q., Gao, L., Guoping Zhao*.. Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting nerve repair via the TLR4/NF-kappaB pathway [J]. CNS Neurosci Ther, 2023.

（4）Si W. M., Li, X., Jing, B., Chang, S. Q., Zheng, Y. C., Chen, Z. N., Guoping Zhao*., Zhang, D*. Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain [J]. Phytotherapy Research, 2023.

（5）Li X., Zhang, D., Shi, H., Jing, B., Chen, Z., Zheng, Y., Chang, S., Gao, L., Guoping Zhao*.. Identification of pyroptosis‑related genes in neuropathic pain based on bioinformatics analysis [J]. Exp Ther Med, 2023, 25(1): 46.

（6）Li X., Shi, H. M., Zhang, D., Jing, B., Chen, Z. N., Zheng, Y. C., Chang, S. Q., Gao, L., Guoping Zhao*.. Paeonol alleviates neuropathic pain by modulating microglial M1 and M2 polarization via the RhoA/p38MAPK signaling pathway [J]. Cns Neuroscience & Therapeutics, 2023, 29(9): 2666-79.

（7）Bei Jing Zhen-ni Chen, Wai-mei Si,, Jia-ji Zhao,Guoping Zhao*., DiZhang*. (+)-Catechin alleviates CCI-induced neuropathic pain in rats by modulating the IL34/CSFIR axis and attenuating the Schwann cell-macrophage cascade response in the DRG [J]. Molecular Neurobiology, 2023.

（8）Zhang D., Li, X., Jing, B., Shi, H., Chang, S., Chen, Z., Zheng, Y., Pan, Y., Qian, G., Guoping Zhao*. Identification of pathways and key genes in male late-stage carotid atherosclerosis using bioinformatics analysis [J]. Exp Ther Med, 2022, 24(1): 460.

（9）Zhang D., Jing, B., Li, X., Shi, H. M., Chen, Z. N., Chang, S. Q., Zheng, Y. C., Lin, Y., Pan, Y. W., Sun, J. X., Guoping Zhao*. Antihyperalgesic Effect of Paeniflorin Based on Chronic Constriction Injury in Rats [J]. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy, 2022, 32(3): 375-85.

（10）Zhang D., Jing, B., Chen, Z., Li, X., Shi, H., Zheng, Y., Chang, S., Guoping Zhao*.. Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway [J]. Phytomedicine, 2022, 106: 154420.

（11）Zhang D., Chang, S., Li, X., Shi, H., Jing, B., Chen, Z., Lin, Y., Zheng, Y., Qian, G., Pan, Y., Guoping Zhao*. Therapeutic effect of paeoniflorin on chronic constriction injury of the sciatic nerve via the inhibition of Schwann cell apoptosis [J]. Phytother Res, 2022, 36(6): 2572-82.

（12）Chang S. Q., Li, X., Zheng, Y. C., Shi, H. M., Zhang, D., Jing, B., Chen, Z. N., Qian, G. Q., Guoping Zhao*. Kaempferol exerts a neuroprotective effect to reduce neuropathic pain through TLR4/NF-kappa B signaling pathway [J]. Phytotherapy Research, 2022, 36(4): 1678-91.

（13）Chang S. Q., Huang, Y. L., Zhang, D., Sun, J. X., Yang, B., Lin, Y., Li, X., Jing, B., Shi, H. M., Zheng, Y. C., Zhang, C. L., Chen, F. G., Qian, G. Q., Guoping Zhao*. Mechanism of Ginsenoside Rb1 Modulating the Glycolipid Metabolism in Rats with Metabolic Syndrome [J]. International Journal of Pharmacology, 2022, 18(2): 331-45.

（14）Zhang D., Yang, B., Chang, S. Q., Ma, S. S., Sun, J. X., Yi, L., Li, X., Shi, H. M., Jing, B., Zheng, Y. C., Zhang, C. L., Chen, F. G., Guoping Zhao*. Protective effect of paeoniflorin on H(2)O(2) induced Schwann cells injury based on network pharmacology and experimental validation [J]. Chin J Nat Med, 2021, 19(2): 90-9.

（15）Zhang D., Sun, J., Chang, S., Li, X., Shi, H., Jing, B., Zheng, Y., Lin, Y., Qian, G., Pan, Y., Guoping Zhao*. Protective effect of 18beta-glycyrrhetinic acid against H(2)O(2)-induced injury in Schwann cells based on network pharmacology and experimental validation [J]. Exp Ther Med, 2021, 22(5): 1241.

（16）Zhang D., Chang, S. Q., Jing, B., Li, X., Shi, H. M., Zheng, Y. C., Lin, Y., Chen, Z. N., Qian, G. Q., Pan, Y. W., Guoping Zhao*. Reactive Oxygen Species Are Essential for Vasoconstriction upon Cold Exposure [J]. Oxidative Medicine and Cellular Longevity, 2021, 2021.

（17）Yang B., Ma, S., Zhang, C., Sun, J., Zhang, D., Chang, S., Lin, Y., Guoping Zhao*. Higenamine Attenuates Neuropathic Pain by Inhibition of NOX2/ROS/TRP/P38 Mitogen-Activated Protein Kinase/NF-κB Signaling Pathway [J]. Front Pharmacol, 2021, 12: 716684.

獲獎及榮譽

（1）趙國平(4/4); 國家中醫藥管理局中醫藥基礎研究獎, 國家中醫藥管理局, 科技進步, 省部一等獎, 1998(彭懷仁; 孫世發; 王旭東; 趙國平)

（2）趙國平(4/4); 國家科技進步三等獎, 中華人民共和國科技部,國家級三等獎, 1999(彭懷仁; 孫世發; 王旭東; 趙國平)

（3）趙國平(1/1); 江蘇省要突出貢獻中青年專家稱号, 江蘇省人民政府, 江蘇省有突出貢獻中青年專家, 省部一等獎, 2005(趙國平)

（4）趙國平 (1/3); 《中藥大辭典》第二版獲第二屆中國出版政府獎圖書獎, 國家新聞出版總署, 《中藥大 辭典》（第二版）, 省部一等獎, 2010(趙國平; 戴慎; 陳仁壽 ) (科研獎勵)

（5）趙國平(1/1) 第七批全國老中醫藥專家學術經驗繼承指導老師，2022

學術兼職

廣東省中醫藥學會理事

中華中醫藥學會中醫免疫分會常務理事

中共湛江市委保健委員會保健專家